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Uses
Side effects
Interactions
Precautions
- RAZADYNE ER and RAZADYNE is a cholinesterase inhibitor indicated for the treatment of mild to moderate dementia of the Alzheimer’s type
- The most common adverse reactions (≥5%) were nausea, vomiting, diarrhea, dizziness, headache, and decreased appetite
- Potential to interfere with the activity of anticholinergic medications
- Synergistic effect expected when given concurrently with succinylcholine, other cholinesterase inhibitors, similar neuromuscular blocking agents, or cholinergic agonists
- Serious skin reactions: discontinue at first appearance of skin rash
- All patients should be considered at risk for adverse effects on cardiac conduction, including bradycardia and AV block, due to vagotonic effects on sinoatrial and atrioventricular nodes
- Active or occult gastrointestinal bleeding: monitor, especially those with an increased risk for developing ulcers
- Cholinomimetics may cause bladder outflow obstruction
- Monitor for respiratory adverse events in patients with a history of severe asthma or obstructive pulmonary disease
