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Uses
Side effects
Interactions
Precautions
STARLIX (nateglinide) is a glinide indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. (1)
Limitations of use: Not for treating type 1 diabetes mellitus or diabetes ketoacidosis (1)
Common adverse reactions associated with STARLIX (3% or greater incidence) were upper respiratory tract infection, back pain, flu symptoms, dizziness, arthropathy, diarrhea. (6.1)
- Drugs That May Increase the Potential for Hypoglycemia: STARLIX dose reductions and increased frequency of glucose monitoring may be required when co-administered (7)
- Drugs That May Increase the Potential for Hyperglycemia: STARLIX dose increases and increased frequency of glucose monitoring may be required when co-administered (7)
- Drugs That May Blunt Signs and Symptoms of Hypoglycemia: Increased frequency of glucose monitoring may be required when coadministered (7)
- Hypoglycemia: STARLIX may cause hypoglycemia. Administer before meals to reduce the risk of hypoglycemia. Skip the scheduled dose of STARLIX if a meal is skipped to reduce the risk of hypoglycemia. (5.1) Macrovascular outcomes: There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with STARLIX. (5.2)
