Clinical Insight Integrating PGx Testing to Enhance Clinical Confidence and Reduce Patient Risk In modern medicine, the pressure on clinicians has never been greater. Patient complexity is increasing, time is always limited, and the demand for evidence-based, personalized care is the new benchmark. While we have more therapeutic options than ever, the fundamental challenge of prescribing remains: how can we be confident that Read
Clinical Insight The MTHFR Question: An Evidence-Based Guide for Clinicians on Folate Metabolism and Medication Response It’s a question more clinicians are hearing in their practice: “I think I have the MTHFR mutation. What does that mean for my health?” Driven by direct-to-consumer genetic testing and online health forums, patients are increasingly aware of the MTHFR gene. While this awareness can lead to confusion, it Read
Clinical Insight Precision in Pediatrics: Using Pharmacogenetics to Safely Navigate Psychiatric Prescribing for Children & Adolescents Prescribing psychiatric medication for a child or adolescent is one of the most considered decisions a clinician can make. The responsibility is immense, and the process is often fraught with uncertainty for providers, parents, and the young patients themselves. Unlike in adult medicine, you are working with a developing system Read
Clinical Insight Navigating Polypharmacy: How Genetic Testing Can De-Risk Prescribing for Patients on Multiple Medications For any clinician managing patients with co-morbid conditions, polypharmacy is the norm. It’s a delicate balancing act of therapeutic goals, but each new prescription added to the regimen increases the risk of a cascade of negative outcomes: drug-drug interactions, adverse drug reactions (ADRs), and therapeutic failures. Standard interaction checkers Read
Clinical Insight Poor Metabolizer vs. Ultra-Rapid: A Clinician's Guide to PGx-Informed Dosing Strategies The clinical mantra of "start low, go slow" has long guided prescribing, but it's an approach born from necessity, not precision. It’s a tacit acknowledgment that patients metabolize medications at vastly different rates. What if you could know a patient's metabolic capacity before Read
Clinical Insight Precision Over Guesswork: The Clinical Value of PGx Testing for Medication Matching Introduction As a provider, you understand that every patient responds differently to treatment—especially when it comes to medications. Whether managing depression, anxiety, ADHD, chronic pain, or cardiovascular conditions, the challenge remains the same: finding the right medication at the right dose, without unnecessary trial and error. Pharmacogenetic (PGx) testing Read
Clinical Insight Leveraging ClarityX® Clinical Pharmacists for Confident Prescribing Introduction Pharmacogenetic (PGx) testing delivers powerful insights—but interpreting those insights and translating them into patient care decisions can sometimes raise some questions, especially for providers new to PGx. At ClarityX®, we believe clinical support shouldn’t end when the report is delivered. That’s why every provider who orders Read
Clinical Insight ClarityX® vs. Insurance Labs: Choosing the Better Path for PGx Testing Introduction When it comes to pharmacogenetic (PGx) testing, the provider’s intent is simple: identify the right medication for the patient based on their genetic profile. But the path to achieving that goal can vary dramatically depending on the lab you choose. If you’ve ever ordered a PGx test Read
Clinical Insight Identifying Ideal Candidates for Pharmacogenetic (PGx) Testing Introduction: Pharmacogenetic (PGx) testing is a valuable clinical tool—but knowing when to use it and with whom is just as important as understanding how it works. Many providers recognize the benefits of personalized prescribing but aren’t always sure which patients will benefit most from PGx testing. This insight Read