Discover how genetics may impact your medications

The COMT gene, also known as catechol-O-methyltransferase, plays a crucial role in the regulation of neurotransmitters in the brain. This gene is involved in the breakdown of catecholamines, including dopamine and norepinephrine, which are essential for various cognitive functions. Variations in the COMT gene have been associated with several health

Introduction The human body is a complex and dynamic system where numerous chemical reactions take place continuously to maintain its functionality. One crucial aspect of these processes is drug metabolism, which involves the transformation of pharmaceutical compounds into active or inactive metabolites. Metabolism refers to how your body changes a

Introduction One of the most important genes involved in drug metabolism is CYP2D6. CYP2D6 is one of the genes associated with Cytochrome P450 (CYP) system. The Cytochrome P450 system is a group of enzymes responsible for metabolizing a wide range of substances in the human body. The CYP system is

Introduction Pharmacogenetics and pharmacogenomics are both integral to the field of personalized medicine, which seeks to tailor medical treatment to individual patients based on their unique genetic makeup. Pharmacogenetics focuses on the study of how an individual's genetic variation affects their response to specific drugs. By understanding how genetics impact

Every time your heart beats, it pushes blood through your veins, arteries, and capillaries so they can transport the blood to the rest of your body. When you have normal blood pressure levels, your system functions perfectly. However, if you suffer from high blood pressure levels, your body has to

Have you or your children ever experienced challenges with focus, impulsivity, and inability to gather thoughts in the course of everyday life? Has the question ever surfaced that there may be a medical diagnosis to explain these symptoms? Attention deficit/ hyperactivity disorder (ADHD) may be the culprit for these disrupted

Introduction In this day and age, it is inevitable for people to experience anxiety on occasion. However, there are individuals that deal with debilitating symptoms from diagnosed anxiety disorders. Anxiety disorders can make it very difficult to function normally; paralyzed by the fear of the unknown. One’s life can

Introduction to Pharmacogenomics Several factors may contribute to how an individual can respond to medications such as gender, age, and diet. However, a person’s unique genetic makeup can also provide insight into how they may respond to medications.  Pharmacogenomics is the compilation of research involving the relationship between genetic

Introduction Pharmacogenomics is not a new concept, but it is becoming more well-known. We already know that each person is unique. Our uniqueness is readily visible in most; our eyes, hair, height, weight, and skin tone all differ. We also know that sometimes you and your parents or siblings have

Introduction Deoxyribonucleic acid, DNA, is the alphabet of our bodies. Genes are the paragraphs written by our DNA to give direction for each enzyme or protein produced. These proteins are then used to form all aspects of the body. The study of how our genes affect our medications is called

What is the MTHFR gene? The MTHFR gene impacts health in multiple ways; including mental health, heart disease, diabetes, and cancer. Knowing how your body functions can help you make better choices and live a healthier life. For example, knowing your genetics may help your physician better determine which medications

There are an estimated 350 million people all over the world that are debilitated by major depressive disorder (MDD).1 In the midst of the COVID-19 global pandemic it has been studied that the incidence of depression in the United States is 3 times higher compared to rates prior to

From headaches and muscle aches to post-surgery complications and chronic pain conditions, there’s no shortage of reasons why someone might seek pain management drugs. While medication can bring relief, it can also bring negative side effects that are even worse than the pain itself. Of the 170 million Americans

Everybody’s received a cholesterol test at some point in their life. Cholesterol, a waxy organic molecule made by the liver and found in many foods, is necessary for your body. However, too much cholesterol can end up being detrimental to your health. In the United States, over 93 million

It’s normal for your heart rate to escalate a bit after an exercise session or before a nerve-wracking event. However, if your heart rate seems irregular or rapid for no discernible reason, it may be indicative of a larger issue. Between 2.7 and 6.1 million Americans have